What has research taught us?

Here we bring together fascinating research, clinical insights and real-life case studies on Paget's disease. From ancient evidence of the disease to unusual cases, genetics and the latest discoveries, there's plenty to explore and discover how our understanding of Paget's disease continues to evolve.

Impact of research supported by the Paget’s Association

Prof Layfield summarises how wide-ranging and impactful some of the research funded by the Paget’s Association has been in recent years

Disease mechanisms and models

What goes wrong inside bone cells? Investigating the mechanisms and models of Paget's disease enhances our comprehension of the disorder, opening avenues for groundbreaking therapeutic interventions

Paget's genetics

A new gene associated with the disease revealed and molecular testing funded by the Association could enable earlier diagnosis of rare cancer

Epidemiology and patient experience

This section includes research funded by the Association into: the incidence of Paget's in the UK; Vitamin D; side effects of bisphosphonate infusions; clinical presentation; and intensive versus symptomatic treatment

Ancient Paget’s disease

Research funding by The Paget's Association enabled scientists to unravel an 800-year-old mystery associated with Paget's disease. Photo - Norton Priory

Unusual Paget's

We explore some unusual reports of Paget's

Is there a link between Paget's and coal?

Could changes in energy use, particularly coal, be a key factor in the mysterious decline in Paget's disease?

Paget's case studies

Asymptomatic discovery and rare neurological complications

Paget’s in the US

Paget’s disease in the US: A veteran population

Paget’s disease in Portugal

This Portuguese cohort highlights the importance of geographic patterns

Research we fund

The Paget's Association funds many aspects of research into Paget's disease as well as educational projects.

Discover some of the many projects we have funded.

Discover research funded by the Paget's Association

Help us make a difference

Your donations help us to change the lives of those with Paget’s Disease and every donation, no matter how small, is appreciated.

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Shared experiences survey

Your perspective matters!

Have you completed our shared experiences survey?

If you’re living with Paget’s Disease of Bone, we’d love to hear from you. Our anonymous survey explores shared experiences - things like occupation, environment and diet. It is purely for interest to see if we can spot common themes.

In due course, we intend to publish a summary, with responses anonymised, in our Paget’s News magazine. You may have received the survey by email or seen it in our magazine or on Facebook. Please only complete it once.

Complete the survey