Funding research into disease mechanisms and models

Research funded by the Paget's Association provides a better understanding of disease mechanisms underpins improved diagnosis, monitoring and treatments for Paget’s disease.

[2023-2024] Engineering a Paget’s stem cell bank

The Paget's Association funded research at the University of Nottingham to engineer a Paget’s disease stem cell bank

[2019-2024] Studying immune responses

Research taking place in Middlesbrough, funded by the Paget's Association is studying immune responses in Paget's disease

[2021-2023] Developing a 3D bone model

Professor Philippa Hulley and Dr Helen Knowles summarise their fascinating project to develop a fully human 3D bone model of Paget’s disease

[2020-2021] Excessive bone formation in Paget's disease

Dr Daroszewska explains below research funded by the Paget’s Association to help us understand excessive bone formation in Paget's disease

[2019-2020] Examining changes in bone geometry and bone strength

The Sir Julian Paget Student Research Bursary was awarded to Alisha Sharma to assessment sexually dimorphic bone shape and vascular alterations as indicators of Paget’s disease

[2017-2018] Targeting autophagy in Paget's disease

The work conducted as a result of a Paget's Association Student Bursary Award has revealed a previously unknown mechanism of action of bisphosphonates, in that they might also have the potential to stimulate autophagy

[2016-2017] Paget's and bone cancer: the application of RNA biology

The Allan Reid Student Research Bursary was awarded to Darrell Green by the Paget's Association to research osteosarcoma and Paget's disease