Pamidronate is an effective treatment but has largely been superseded by zoledronate (zoledronic acid) which lasts longer and is easier to administer.
Pamidronate is given in several doses, intravenously and repeated when necessary, depending on symptoms. Doses can vary, but commonly 60mg is given by an infusion and this is repeated on 3 consecutive days.
Pamidronate: given intravenously over 2-4 hours. Dosage (60 – 90 mg) and frequency will depend on the severity of symptoms.